It’s been quite some time since Castlevania: Lords of Shadow’s release, and since then, fans have been debating back and forth over Mercury Steam’s ‘vania opus being part of the series’ official canon. Now, I’m happy to report that that debate can come to an end.
David Cox, the producer of the game, has just stated (as a response to this very question) via Twitter that: “It’s not part of the official timeline. This is a new/alternate timeline.” This signifies the notion that Mercury Steam is free to flex their creative muscles with the franchise, without having to set restrictions due to what’s already set in stone in the main timeline. So, it seems like a Lords of Shadow sequel where we actually play as Dracula himself taking on hordes of Satan’s acolytes and other creatures of the night isn’t totally out of the realm of possibility.
[Source]